Description

3-(Pyrrolidine-1-Carbonyl)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is a sophisticated bicyclic organic compound featuring both a carboxylic acid and a pyrrolidine amide functional group, making it a versatile and valuable chiral building block. Its unique norbornene-derived scaffold provides a rigid, three-dimensional structure that is highly sought after for constructing complex molecular architectures in advanced research and development. This compound is primarily utilized by pharmaceutical and agrochemical R&D teams, as well as academic researchers, for applications in medicinal chemistry, asymmetric synthesis, and the development of novel catalysts and materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its rigid bicyclic structure for enhanced bioactivity.
• Catalyst & Ligand Development: Acts as a precursor for novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or cross-linking agent for creating specialty polymers with unique thermal and mechanical properties.
• Academic & Discovery Chemistry: A valuable tool for exploring new chemical spaces and reaction methodologies in synthetic organic chemistry laboratories.
• Peptidomimetics & Bioisosteres: Its structure is used to design and synthesize conformationally constrained peptide analogs for drug discovery.

Basic Information

Product Name	3-(Pyrrolidine-1-Carbonyl)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid
CAS No.	436811-25-5
Molecular Formula	C14H19NO3
Molecular Weight	249.31 g/mol
Synonyms	3-(1-Pyrrolidinecarbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; 2-Norbornene-2-carboxylic acid, 3-(1-pyrrolidinylcarbonyl)-; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-(1-pyrrolidinylcarbonyl)-; 3-(Pyrrolidine-1-carbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; 436811-25-5; 3-(Pyrrolidin-1-ylcarbonyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-(Pyrrolidine-1-Carbonyl)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.