Description

4-(2-Methyl-2,3-Dihydro-1H-Indol-1-Yl)-4-Oxobutanoic Acid is a specialized organic compound featuring a functionalized indoline core linked to a butanoic acid moiety. This unique structure makes it a valuable key intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily sought by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold or precursor in the research and development of new APIs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Bioconjugation & Prodrug Synthesis: The carboxylic acid group enables conjugation strategies for creating targeted drug delivery systems or prodrugs.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides.

Basic Information

Product Name	4-(2-Methyl-2,3-Dihydro-1H-Indol-1-Yl)-4-Oxobutanoic Acid
CAS No.	436091-51-9
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	4-(2-Methyl-2,3-dihydro-1H-indol-1-yl)-4-oxobutanoic acid; 4-(2-Methylindolin-1-yl)-4-oxobutanoic acid; 1-(3-Carboxypropionyl)-2-methylindoline; Butanoic acid, 4-(2-methyl-2,3-dihydro-1H-indol-1-yl)-4-oxo-; 2-Methyl-1-(3-carboxypropionyl)indoline; 4-Oxo-4-(2-methyl-2,3-dihydro-1H-indol-1-yl)butyric acid
EINECS	Contact for details

Quality Control

Our production of 4-(2-Methyl-2,3-Dihydro-1H-Indol-1-Yl)-4-Oxobutanoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications, and our quality system is designed to meet the rigorous standards of global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is stable under these conditions but should be kept away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.