Description

2,3'-Dibromo-4'-Fluoroacetophenone, 97% is a high-purity, multi-halogenated acetophenone derivative, serving as a critical building block in advanced organic synthesis. Its precise halogen substitution pattern makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the fluorine and bromine atoms can enhance binding and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in Suzuki, Stille, or other cross-coupling reactions to introduce functionalized aryl groups into target molecules.
• Chemical Research & Development: A versatile reagent for method development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	2,3'-Dibromo-4'-Fluoroacetophenone, 97%
CAS No.	435273-49-7
Molecular Formula	C8H5Br2FO
Molecular Weight	295.93 g/mol
Synonyms	1-(2,3-Dibromo-4-fluorophenyl)ethan-1-one; 2',3-Dibromo-4'-fluoroacetophenone; 4'-Fluoro-2,3'-dibromoacetophenone; 2,3-Dibromo-4-fluoroacetophenone; α,2,3-Tribromo-4-fluoroacetophenone (common misnomer); DBFA (abbreviation); Acetophenone, 2,3'-dibromo-4'-fluoro-; 435273-49-7 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 2,3'-Dibromo-4'-Fluoroacetophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure the stated purity of 97% (minimum) and confirm identity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.