Description

1,5-Methanopentalen-4(1H)-One, Hexahydro-3,6A-Dihydroxy-1,7,7-Trimethyl-, (1S,3R,3As,5S,6Ar)- (9Ci) is a high-purity, stereochemically defined advanced intermediate with significant synthetic utility. This compound matters for its role as a key chiral building block in the synthesis of complex natural products and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in process development and the production of high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of novel drug candidates and complex therapeutic agents.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct stereogenic centers with high enantiomeric purity.
• Natural Product Synthesis: Acts as a core structural motif or precursor in the total synthesis of terpenoids and other complex natural compounds.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the efficient, scalable production of target molecules.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring new synthetic methodologies and reaction pathways.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in related synthetic processes.

Basic Information

Product Name	1,5-Methanopentalen-4(1H)-One, Hexahydro-3,6A-Dihydroxy-1,7,7-Trimethyl-, (1S,3R,3As,5S,6Ar)- (9Ci)
CAS No.	434342-98-0
Molecular Formula	C12H20O3
Molecular Weight	212.29 g/mol
Synonyms	(1S,3R,3aS,5S,6aR)-Hexahydro-3,6a-dihydroxy-1,7,7-trimethyl-1,5-methanopentalen-4(1H)-one; (1S,3R,3aS,5S,6aR)-Hexahydro-3,6a-dihydroxy-1,7,7-trimethyl-1,5-methanopentalen-4(1H)-one (9CI); 1,5-Methanopentalen-4(1H)-one, hexahydro-3,6a-dihydroxy-1,7,7-trimethyl-, (1S,3R,3aS,5S,6aR)-; 434342-98-0; (1S,3R,3aS,5S,6aR)-3,6a-Dihydroxy-1,7,7-trimethylhexahydro-1,5-methanopentalen-4(1H)-one
EINECS	Contact for details

Quality Control

Our 1,5-Methanopentalen-4(1H)-One, Hexahydro-3,6A-Dihydroxy-1,7,7-Trimethyl-, (1S,3R,3As,5S,6Ar)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.