Description

1,3-Dibromo-5-(Difluoromethoxy)Benzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both bromine and fluorine substituents, making it a versatile precursor for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring fluorinated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the difluoromethoxy and bromine groups impart specific biological activity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with unique electronic or optical properties.
• Organic Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functionalized aromatic rings into target molecules.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1,3-Dibromo-5-(Difluoromethoxy)Benzene
CAS No.	433939-48-1
Molecular Formula	C7H4Br2F2O
Molecular Weight	305.91 g/mol
Synonyms	5-(Difluoromethoxy)-1,3-dibromobenzene; 1,3-Dibromo-5-(difluoromethoxy)benzene; Benzene, 1,3-dibromo-5-(difluoromethoxy)-; 3,5-Dibromophenyl difluoromethyl ether
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-5-(Difluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.