Description

Cyclooctanol, 2-Fluoro-, (1R,2R)- (9Ci) is a high-purity, stereochemically defined fluorinated cyclooctanol derivative. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and agrochemicals. It is essential for research and production in fine chemical, pharmaceutical, and specialty material sectors where precise stereochemistry and fluorine substitution are critical for modulating biological activity and material properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science: Investigated as a monomer or modifier for creating specialized polymers and liquid crystals with unique optical or electronic properties.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry, including novel fluorination and ring-expansion reactions.

Basic Information

Product Name	Cyclooctanol, 2-Fluoro-, (1R,2R)- (9Ci)
CAS No.	433305-17-0
Molecular Formula	C8H15FO
Molecular Weight	146.20 g/mol
Synonyms	(1R,2R)-2-Fluorocyclooctanol; (1R,2R)-2-Fluoro-cyclooctan-1-ol; trans-2-Fluorocyclooctanol; 2-Fluorocyclooctanol, (1R,2R)-; Fluorocyclooctanol; Cyclooctanol, 2-fluoro-, (1R-trans)-; 433305-17-0; (1R,2R)-rel-2-Fluorocyclooctanol
EINECS	Contact for details

Quality Control

Every batch of (1R,2R)-2-Fluorocyclooctanol is produced under strict quality management protocols. We employ advanced analytical techniques, including chiral HPLC, GC, NMR, and MS, to ensure identity, purity, and enantiomeric excess meet exacting customer requirements. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality systems support compliance with cGMP, ISO, and other relevant regulatory standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.