Description

4-Methyl-7-[4-Nitro-2-(Trifluoromethyl)Phenoxy]Chromen-2-One is a specialized fluorinated coumarin derivative, a high-value intermediate in advanced organic synthesis. Its molecular architecture, featuring both a nitro group and a trifluoromethyl substituent, makes it a critical building block for developing compounds with specific electronic and steric properties. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, where the nitro and trifluoromethyl groups contribute to biological activity and environmental persistence profiles.
• Material Science: Acts as a monomer or functional additive in the creation of advanced polymers, coatings, and organic electronic materials that benefit from its light-absorbing and electron-withdrawing characteristics.
• Fluorescent Probe Synthesis: Utilized as a core structure for developing sensitive fluorescent dyes and molecular probes used in biochemical assays and diagnostic imaging.
• Organic Synthesis Building Block: Provides a versatile scaffold for medicinal and combinatorial chemistry, enabling the exploration of new chemical space in lead optimization programs.

Basic Information

Product Name	4-Methyl-7-[4-Nitro-2-(Trifluoromethyl)Phenoxy]Chromen-2-One
CAS No.	433254-36-5
Molecular Formula	C₁₇H₁₀F₃NO₅
Molecular Weight	365.26 g/mol
Synonyms	4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)-2H-chromen-2-one; 4-Methyl-7-(4-nitro-2-trifluoromethylphenoxy)coumarin; 7-((4-Nitro-2-(trifluoromethyl)phenyl)oxy)-4-methyl-2H-1-benzopyran-2-one; 4-Methyl-7-(4-nitro-2-(trifluoromethyl)phenoxy)coumarin; 2H-1-Benzopyran-2-one, 7-((4-nitro-2-(trifluoromethyl)phenyl)oxy)-4-methyl-
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-7-[4-Nitro-2-(Trifluoromethyl)Phenoxy]Chromen-2-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as identity, purity, and impurity profiles to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.