Description

2,4-Dichloro-5-Methoxyphenylboronic Acid is a versatile and highly functionalized boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, which is essential for constructing complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides and fungicides with specific activity, leveraging the dichloro and methoxy substituents for targeted bioactivity.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized to create boronic acid-based sensors and probes for detecting sugars or other diol-containing biomolecules.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke organic compounds for clients.

Basic Information

Product Name	2,4-Dichloro-5-Methoxyphenylboronic Acid
CAS No.	431942-67-5
Molecular Formula	C7H7BCl2O3
Molecular Weight	220.85 g/mol
Synonyms	(2,4-Dichloro-5-methoxyphenyl)boronic acid; 2,4-Dichloro-5-methoxybenzeneboronic acid; 5-Methoxy-2,4-dichlorophenylboronic acid; B-(2,4-Dichloro-5-methoxyphenyl)boronic acid; 431942-67-5; 2,4-Dichloro-5-methoxy-phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dichloro-5-Methoxyphenylboronic Acid is manufactured and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity. Our standard grade typically meets a purity specification of ≥95% (by HPLC), with options for higher grades (≥97%, ≥98%) available. Comprehensive analytical testing, including HPLC, NMR, and FTIR, is performed to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.