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Dichloro{(1R,2R)-N,n-Bis[2-(Diphenylphosphino)Benzyl]Cyclohexane-1,2-Diamine}Ruthenium(Ii), Min. 97% CAS NO 429678-11-5


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CAS No.:429678-11-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dichloro{(1R,2R)-N,n-Bis[2-(Diphenylphosphino)Benzyl]Cyclohexane-1,2-Diamine}Ruthenium(II), Min. 97% is a high-purity, chiral ruthenium complex featuring a sophisticated P,N,N,P tetradentate ligand system. This compound is a highly valuable and selective catalyst for asymmetric hydrogenation and other transition metal-catalyzed organic transformations. It is essential for R&D chemists and process engineers in the pharmaceutical, fine chemical, and agrochemical industries who require precise stereocontrol in the synthesis of chiral intermediates and active ingredients.

Application

  • Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral ketones, imines, and olefins to produce chiral alcohols, amines, and other building blocks.
  • Pharmaceutical Intermediate Synthesis: Enables the efficient and stereoselective construction of complex molecules for active pharmaceutical ingredients (APIs).
  • Fine Chemical Production: Used in the synthesis of specialty chemicals, flavors, and fragrances where high enantiomeric purity is critical.
  • Methodology Development: A key reagent in academic and industrial research for developing new catalytic asymmetric reactions.
  • Agrochemical Synthesis: For the production of chiral herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
  • Transfer Hydrogenation: Can be employed in reactions using alternative hydrogen donors like isopropanol or formic acid.

Basic Information

Product Name Dichloro{(1R,2R)-N,n-Bis[2-(Diphenylphosphino)Benzyl]Cyclohexane-1,2-Diamine}Ruthenium(II), Min. 97%
CAS No. 429678-11-5
Molecular Formula C46H48Cl2N2P2Ru
Molecular Weight 872.80 g/mol
Synonyms (1R,2R)-N,N-Bis[2-(Diphenylphosphino)benzyl]cyclohexane-1,2-diamine Dichlororuthenium(II); RuCl2[(R,R)-Ph-BPE]; Dichloro[(R,R)-Ph-BPE]ruthenium(II); (R,R)-Ph-BPE RuCl2; Ruthenium(II) dichloride complex with (1R,2R)-N,N-Bis[2-(diphenylphosphino)benzyl]-1,2-cyclohexanediamine; Chiral Ru-BPE Catalyst; Asymmetric Hydrogenation Catalyst (Ru, BPE ligand).
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Quality Control

Our Dichloro{(1R,2R)-N,n-Bis[2-(Diphenylphosphino)Benzyl]Cyclohexane-1,2-Diamine}Ruthenium(II) is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure performance consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain catalytic activity and purity.

Specification

Item Specification
Appearance Orange to red-brown crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) Min. 97.0%
Chiral Purity Min. 99.0% ee (by chiral HPLC)
Residual Solvents (GC) Meets ICH guidelines
Heavy Metals < 20 ppm
Water Content (KF) < 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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