Description

1,3,2-Dioxaborolane, 2-(4-Methoxy-2,5-Dimethylphenyl)-4,4,5,5-Tetramethyl- is a high-purity, functionalized boronic ester derivative, serving as a critical synthetic intermediate. Its value lies in providing a protected, air-stable boronic acid equivalent for advanced cross-coupling reactions, enabling the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides requiring specific aryl-boron motifs.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for bio-conjugation and imaging.
• Custom Fine Chemical Synthesis: A versatile reagent for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-(4-Methoxy-2,5-Dimethylphenyl)-4,4,5,5-Tetramethyl-
CAS No.	428517-49-1
Molecular Formula	C₁₇H₂₇BO₃
Molecular Weight	290.21 g/mol
Synonyms	2-(4-Methoxy-2,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methoxy-2,5-dimethylbenzeneboronic acid pinacol ester; (4-Methoxy-2,5-dimethylphenyl)boronic acid pinacol ester; 2-(4-Methoxy-2,5-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (4-Methoxy-2,5-dimethylphenyl)boronate; 4-Methoxy-2,5-dimethylphenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 2-(4-Methoxy-2,5-Dimethylphenyl)-4,4,5,5-Tetramethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided for every shipment, ensuring compliance with our stringent specifications and your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.