Description

3-Chloro-5-Ethoxy-4-Isopropoxybenzaldehyde is a versatile and highly functionalized benzaldehyde derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique substitution pattern makes it a valuable building block for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists engaged in the synthesis of novel active ingredients, fine chemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its aromatic aldehyde functionality for heterocycle formation.
• Liquid Crystal & OLED Materials: Acts as a core building block for synthesizing advanced organic electronic materials, including ligands for metal complexes and components for liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Fine Chemical & Dye Intermediate: Employed in the production of specialized dyes, pigments, and performance chemicals where the chloro, ethoxy, and isopropoxy groups impart specific solubility and reactivity profiles.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological development in organic chemistry, including cross-coupling reactions, nucleophilic aromatic substitution, and as a scaffold for library synthesis in drug discovery.

Basic Information

Product Name	3-Chloro-5-Ethoxy-4-Isopropoxybenzaldehyde
CAS No.	428501-78-4
Molecular Formula	C₁₂H₁₅ClO₃
Molecular Weight	242.70 g/mol
Synonyms	4-Isopropoxy-3-chloro-5-ethoxybenzaldehyde; 3-Chloro-5-ethoxy-4-(1-methylethoxy)benzaldehyde; Benzaldehyde, 3-chloro-5-ethoxy-4-(1-methylethoxy)-; 3-Chloro-4-isopropoxy-5-ethoxybenzaldehyde; 5-Ethoxy-3-chloro-4-isopropoxybenzaldehyde; 4-(Isopropoxy)-3-chloro-5-ethoxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Ethoxy-4-Isopropoxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere for long-term storage). Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.