Description

[1-(2-Fluoro-Benzyl)-Piperidin-2-Yl]-Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine-methanol structure with a fluorinated benzyl substituent. This compound is essential for the synthesis of complex active pharmaceutical ingredients (APIs), offering a critical building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Fine Chemical Synthesis: Serves as a precursor for the production of more complex, fluorinated heterocyclic compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of clinical trial materials.
• Biochemical Research: Potential use as a ligand or modulator in biochemical assays and pharmacological studies.

Basic Information

Product Name	[1-(2-Fluoro-Benzyl)-Piperidin-2-Yl]-Methanol
CAS No.	415712-70-8
Molecular Formula	C13H18FNO
Molecular Weight	223.29 g/mol
Synonyms	2-Fluoro-α-[(2-hydroxyethyl)piperidin-1-ylmethyl]benzene; 1-[(2-Fluorophenyl)methyl]-2-piperidinemethanol; (1-[(2-Fluorobenzyl)piperidin-2-yl])methanol; 415712-70-8; 1-(2-Fluorobenzyl)piperidine-2-methanol; 2-(Hydroxymethyl)-1-(2-fluorobenzyl)piperidine
EINECS	Contact for details

Quality Control

Our [1-(2-Fluoro-Benzyl)-Piperidin-2-Yl]-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.