Description

1,2,4-Trioxane,3,6-Dimethoxy-,(3R,6R)-Rel-(9Ci) is a high-purity, stereochemically defined trioxane derivative, a class of compounds known for their potent biological activity. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key synthetic intermediate or a pharmacophore for novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of new antimalarial, anticancer, and antiparasitic drugs, where its specific stereochemistry is critical for efficacy.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antimalarial compounds and other bioactive molecules.
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold in drug discovery programs targeting parasitic and infectious diseases.
• Chemical Biology Studies: Employed in mechanistic studies to understand the mode of action of trioxane-based therapeutics.
• Academic Research: Utilized in universities and research institutes for the development of new synthetic methodologies and the exploration of structure-activity relationships (SAR).
• High-Purity Reagent: Acts as a specialized reagent for the preparation of stereochemically complex molecules in process chemistry.

Basic Information

Product Name	1,2,4-Trioxane,3,6-Dimethoxy-,(3R,6R)-Rel-(9Ci)
CAS No.	413584-25-5
Molecular Formula	C5H10O5
Molecular Weight	150.13 g/mol
Synonyms	(3R,6R)-3,6-Dimethoxy-1,2,4-trioxane; rel-(3R,6R)-3,6-Dimethoxy-1,2,4-trioxane; 3,6-Dimethoxy-1,2,4-trioxane (rel-(3R,6R)-); Artemisinin derivative intermediate; 1,2,4-Trioxane, 3,6-dimethoxy-, (3R,6R)-rel-; Dimethoxy-trioxane stereoisomer
EINECS	Contact for details

Quality Control

Our 1,2,4-Trioxane,3,6-Dimethoxy-,(3R,6R)-Rel-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, stereochemical identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates, ensuring data integrity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its properties as a strong oxidizer, keep away from heat, sparks, open flames, and incompatible materials such as reducing agents. Handle and store under an inert atmosphere if specified for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.