Description

Rac 6-Fluoro-3,4-Dihydro-2H-1-Benzopyran-2-Carboxaldehyde is a versatile chiral building block and key fluorinated intermediate in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorine atoms and chroman-based scaffolds into target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and cardiovascular diseases.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Chiral Chemistry Research: Serves as a racemic starting material for the study of asymmetric synthesis, resolution techniques, and catalyst development.
• Material Science Precursor: Employed in the creation of specialty polymers and advanced organic materials with tailored optical or electronic properties.
• Fluorine Chemistry Building Block: Essential for introducing the 6-fluoro-chroman motif into more complex molecules during multi-step synthetic routes.

Basic Information

Product Name	Rac 6-Fluoro-3,4-Dihydro-2H-1-Benzopyran-2-Carboxaldehyde
CAS No.	409346-73-2
Molecular Formula	C10H9FO2
Molecular Weight	180.17 g/mol
Synonyms	6-Fluorochroman-2-carboxaldehyde; (±)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carbaldehyde; 2-Formyl-6-fluorochroman; 6-Fluoro-2-chromancarboxaldehyde; 6-Fluorochroman-2-carbaldehyde; rac-6-Fluorochroman-2-carboxaldehyde; 409346-73-2; 6-Fluoro-3,4-dihydro-2H-chromene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our Rac 6-Fluoro-3,4-Dihydro-2H-1-Benzopyran-2-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.