Description

Ethyl 4-Fluoro-1-Naphthoylformate is a high-purity fluorinated naphthoyl derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile molecular scaffold for constructing complex, functionalized aromatic systems. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorination and ester functionality for their synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Organic Synthesis Reagent: A versatile reagent in academic and industrial R&D for introducing the 4-fluoro-1-naphthoyl moiety into more complex molecular architectures via coupling or condensation reactions.
• Fluorescent Dye & Sensor Development: Acts as a precursor in the creation of fluorophores and molecular sensors due to the naphthalene backbone's inherent photophysical properties.

Basic Information

Product Name	Ethyl 4-Fluoro-1-Naphthoylformate
CAS No.	409081-83-0
Molecular Formula	C₁₄H₁₁FO₃
Molecular Weight	246.24 g/mol
Synonyms	Ethyl 4-fluoro-1-naphthoate; 4-Fluoro-1-naphthoic acid ethyl ester; Ethyl 4-fluoronaphthalene-1-carboxylate; 1-Naphthalenecarboxylic acid, 4-fluoro-, ethyl ester; 4-Fluoronaphthalene-1-carboxylic acid ethyl ester; Ethyl 4-fluoronaphthoate; 409081-83-0; NSC 405124
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-Fluoro-1-Naphthoylformate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for advanced R&D and scale-up. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.