Description

Piperidine, 2-(Trimethylsilyl)-, (2S)- (9Ci) is a high-purity, chiral organosilicon building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

This specialized chiral piperidine derivative serves as a versatile synthon in sophisticated chemical synthesis.

• Pharmaceutical Intermediate: A critical building block for the synthesis of chiral drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Organometallic Chemistry: The trimethylsilyl group acts as a protective moiety or a directing group in metal-catalyzed C-H functionalization reactions.
• Agrochemical Research: Employed in the development of novel, enantiomerically pure active ingredients for crop protection.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers or silicon-containing advanced materials.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	Piperidine, 2-(Trimethylsilyl)-, (2S)- (9Ci)
CAS No.	408331-90-8
Molecular Formula	C8H19NSi
Molecular Weight	157.33 g/mol
Synonyms	(2S)-2-(Trimethylsilyl)piperidine; (S)-2-(Trimethylsilyl)piperidine; (-)-2-(Trimethylsilyl)piperidine; L-2-(Trimethylsilyl)piperidine; 2-Trimethylsilylpiperidine, (S)-; Piperidine, 2-(trimethylsilyl)-, (2S)-; 408331-90-8; (S)-2-Trimethylsilylpiperidine
EINECS	Contact for details

Quality Control

Our Piperidine, 2-(Trimethylsilyl)-, (2S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC and GC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.