Description

4'-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Biphenyl-4-Carbonitrile is a high-value, synthetically versatile boronic ester derivative. This compound serves as a critical Suzuki-Miyaura cross-coupling reagent, enabling the efficient construction of complex biaryl systems essential in advanced material and pharmaceutical chemistry. It is primarily sought by pharmaceutical R&D teams and organic synthesis specialists for developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, especially those containing biphenyl or extended π-conjugated systems.
• Material Science Research: Used in the development of organic light-emitting diodes (OLEDs), liquid crystals, and other advanced organic electronic materials.
• Agrochemical Synthesis: Intermediate for creating novel herbicides, fungicides, and plant growth regulators with specific activity profiles.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in palladium-catalyzed cross-coupling reactions and new synthetic pathway exploration.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	4'-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Biphenyl-4-Carbonitrile
CAS No.	406482-72-2
Molecular Formula	C20H22BNO2
Molecular Weight	319.21 g/mol
Synonyms	4-Cyanobiphenyl-4'-boronic acid pinacol ester; [1,1'-Biphenyl]-4-carbonitrile, 4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl-4'-carbonitrile; 4-Cyanophenylboronic acid pinacol ester; 4'-Cyanobiphenyl-4-boronic acid pinacol ester; PINACOL 4'-CYANOBIPHENYL-4-BORONATE
EINECS	Contact for details

Quality Control

Our 4'-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Biphenyl-4-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.