Description

4-(5-Chloropyridin-2-Yl)Benzoic Acid is a high-purity organic building block characterized by its distinct biphenyl-like structure incorporating chloropyridine and benzoic acid moieties. This compound is of significant value in advanced organic synthesis, serving as a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized as a building block for developing molecular probes and biochemical tools.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	4-(5-Chloropyridin-2-Yl)Benzoic Acid
CAS No.	406234-30-8
Molecular Formula	C12H8ClNO2
Molecular Weight	233.65 g/mol
Synonyms	4-(5-Chloro-2-pyridinyl)benzoic acid; 2-(4-Carboxyphenyl)-5-chloropyridine; 5-Chloro-2-(4-carboxyphenyl)pyridine; [1,1'-Biphenyl]-4-carboxylic acid, 5'-chloro-2'-pyridinyl-; Benzoic acid, 4-(5-chloro-2-pyridinyl)-; 5'-Chloro-2'-pyridinyl-[1,1'-biphenyl]-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(5-Chloropyridin-2-Yl)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and commercial synthesis. Our standard quality commitment includes HPLC purity ≥98% (with higher grades available), identity confirmation via spectroscopic methods, and control of specified impurities. A detailed Certificate of Analysis (COA) is supplied with each shipment, and custom specifications can be developed to meet specific project needs, including compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.