Description

4-(N,N-Dimethylaminocarbonyl)Phenylboronic Acid is a specialized organoboron compound featuring a dimethylcarboxamide substituent, which significantly influences its reactivity and solubility profile. This structural motif makes it a valuable building block in modern synthetic chemistry, particularly for cross-coupling reactions that are foundational to pharmaceutical and advanced material development. It is primarily utilized by research institutions and industrial R&D departments engaged in creating novel active pharmaceutical ingredients (APIs), agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of complex biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides that require specific aryl-aryl linkages.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as those for OLEDs or sensors.
• Chemical Biology & Proteomics: Can be employed as a handle for bioconjugation or in the development of boronic acid-based sensors and inhibitors.
• Ligand & Catalyst Development: The dimethylaminocarbonyl group can act as a coordinating site, making it useful in designing novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds on a commercial scale.

Basic Information

Product Name	4-(N,N-Dimethylaminocarbonyl)Phenylboronic Acid
CAS No.	405520-68-5
Molecular Formula	C9H12BNO3
Molecular Weight	193.01 g/mol
Synonyms	[4-(Dimethylcarbamoyl)phenyl]boronic acid; 4-(Dimethylaminocarbonyl)benzeneboronic acid; N,N-Dimethyl-4-boronobenzamide; p-(N,N-Dimethylcarboxamido)phenylboronic acid; B-[4-(Dimethylamino)carbonyl]phenyl]boronic acid; 4-Carbamoylphenylboronic acid, N,N-dimethyl-; 405520-68-5 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-(N,N-Dimethylaminocarbonyl)Phenylboronic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.