Description

Methanone, (4-Fluorophenyl)-1H-Indol-7-Yl- is a specialized organic compound featuring a unique indole-ketone structure with a fluorophenyl substituent, making it a valuable synthetic intermediate. This compound is critical for advanced research and development in medicinal chemistry, where its scaffold is utilized to explore novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds for potential therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new indole-based compounds with optimized pharmacological profiles.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Organic Synthesis: Acts as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for high-throughput screening.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms.

Basic Information

Product Name	Methanone, (4-Fluorophenyl)-1H-Indol-7-Yl-
CAS No.	405275-40-3
Molecular Formula	C15H10FNO
Molecular Weight	239.25 g/mol
Synonyms	(4-Fluorophenyl)(1H-indol-7-yl)methanone; 7-Benzoyl-4-fluoroindole; 1H-Indol-7-yl(4-fluorophenyl)methanone; (4-Fluorophenyl)(1H-indol-7-yl)methanone; 4-Fluorophenyl 1H-indol-7-yl ketone; 7-(4-Fluorobenzoyl)indole; (p-Fluorophenyl)(7-indolyl)ketone
EINECS	Contact for details

Quality Control

Our production of Methanone, (4-Fluorophenyl)-1H-Indol-7-Yl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to comprehensive in-house specifications, which are aligned with cGMP principles for advanced intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.