Description

(S)-Benzyl 3-Formylpiperidine-1-Carboxylate CAS NO 405063-39-0 is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex bioactive molecules, offering a defined stereocenter essential for developing enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) and metabolic disease research.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure APIs and drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Asymmetric Synthesis: Serves as a versatile precursor for constructing complex piperidine-based scaffolds with defined stereochemistry.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Process Chemistry Development: Employed in the scale-up and route scouting for efficient commercial manufacturing of target molecules.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(S)-Benzyl 3-Formylpiperidine-1-Carboxylate
CAS No.	405063-39-0
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	1-CBz-3-Formylpiperidine, (S)-enantiomer; (S)-1-(Benzyloxycarbonyl)-3-formylpiperidine; (S)-N-Carbobenzyloxy-3-formylpiperidine; (S)-3-Formyl-1-(phenylmethoxy)carbonylpiperidine; (S)-Benzyl 3-formyl-1-piperidinecarboxylate; 1-Piperidinecarboxylic acid, 3-formyl-, phenylmethyl ester, (3S)-; (3S)-3-Formyl-1-{[(phenylmethyl)oxy]carbonyl}piperidine
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 3-Formylpiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere to minimize oxidation and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.