Description

4-Benzyloxy-1-Boc-3-Indolecarbaldehyde is a high-purity, multi-functional indole derivative, serving as a critical advanced intermediate in organic synthesis. Its value lies in its dual-protected indole scaffold, which provides orthogonal reactivity for the selective construction of complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel drug candidates and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of indole-based active pharmaceutical ingredients (APIs) and investigational new drugs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that utilize the indole core structure.
• Organic Synthesis: A versatile precursor for palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, to create complex molecular architectures.
• Material Science: Potential monomer or intermediate for the synthesis of specialty polymers and organic electronic materials.
• Academic & Contract Research: A valuable reagent for methodological development and the total synthesis of natural products in university and CRO laboratories.

Basic Information

Product Name	4-Benzyloxy-1-Boc-3-Indolecarbaldehyde
CAS No.	404888-01-3
Molecular Formula	C21H21NO4
Molecular Weight	351.40 g/mol
Synonyms	1-Boc-4-(benzyloxy)-1H-indole-3-carbaldehyde; 1-(tert-Butoxycarbonyl)-4-(benzyloxy)-1H-indole-3-carboxaldehyde; tert-Butyl 4-(benzyloxy)-3-formyl-1H-indole-1-carboxylate; 4-Benzyloxyindole-1,3-dicarboxylic acid 1-tert-butyl ester 3-aldehyde; 4-(Benzyloxy)-1-[(tert-butoxy)carbonyl]-1H-indole-3-carbaldehyde; 404888-01-3; Boc-4-OBn-indole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Benzyloxy-1-Boc-3-Indolecarbaldehyde is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.