Description

Ethanone, 2,2,2-Trifluoro-1-(1H-Indazol-5-Yl)- (9Ci) is a high-purity fluorinated indazole derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecular architectures, particularly for pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the life sciences sector, where it is used to synthesize novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the trifluoroacetyl and indazole motifs for enhanced biological activity and stability.
• Material Science Precursor: Serves as a specialty monomer or precursor for advanced polymers and functional materials with unique fluorinated properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a versatile electrophile or directing group in complex multi-step syntheses.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(1H-Indazol-5-Yl)- (9Ci)
CAS No.	403660-48-0
Molecular Formula	C9H5F3N2O
Molecular Weight	214.15 g/mol
Synonyms	5-(2,2,2-Trifluoroacetyl)-1H-indazole; 1H-Indazol-5-yl trifluoromethyl ketone; 2,2,2-Trifluoro-1-(1H-indazol-5-yl)ethanone; 5-(Trifluoroacetyl)-1H-indazole; Trifluoroacetylindazole; 403660-48-0; 5-Trifluoroacetylindazole
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(1H-Indazol-5-Yl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.