Description

7-(Trifluoromethoxy)-1-Naphthol is a high-value, fluorinated naphthol derivative, distinguished by the presence of a trifluoromethoxy substituent which imparts unique electronic and steric properties. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in the synthesis of complex organic molecules. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Building block for developing next-generation herbicides and pesticides with enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Used in the research and production of fluorinated components for electronic display and lighting applications.
• Polymer Modification: Serves as a functional monomer or additive to introduce fluorinated groups into polymers, altering their surface properties and stability.
• Organic Synthesis & Catalysis: Valuable reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis due to its electron-withdrawing group.
• Dye & Pigment Industry: Intermediate for creating specialized fluorinated colorants with improved lightfastness and chemical resistance.

Basic Information

Product Name	7-(Trifluoromethoxy)-1-Naphthol
CAS No.	403646-58-2
Molecular Formula	C₁₁H₇F₃O₂
Molecular Weight	228.17 g/mol
Synonyms	1-Naphthol, 7-(trifluoromethoxy)-; 7-(Trifluoromethoxy)naphthalen-1-ol; 7-Trifluoromethoxy-1-naphthol; 7-(Trifluoromethoxy)-1-hydroxynaphthalene; α-Naphthol, 7-trifluoromethoxy derivative; 1-Hydroxy-7-(trifluoromethoxy)naphthalene; 403646-58-2; 7-TFMN
EINECS	Contact for details

Quality Control

Our production of 7-(Trifluoromethoxy)-1-Naphthol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.