Description

4-Pentynoicacid,2-Amino-2-Methyl-,(2R)-(9Ci) is a chiral, non-natural amino acid derivative featuring both an alkyne and a carboxylic acid functional group, making it a versatile building block for advanced synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and novel materials, enabling the construction of complex molecular architectures through click chemistry and peptide coupling. Industries that need it include pharmaceutical R&D for drug discovery, agrochemical research for novel active ingredients, and academic institutions focused on organic and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of potential drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific stereochemistry for activity.
• Peptidomimetics & Bioconjugation: The alkyne group enables efficient, site-specific bioconjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for labeling proteins, antibodies, and other biomolecules.
• Material Science: Acts as a monomer or cross-linker precursor for creating functional polymers with tailored properties.
• Academic & Contract Research: A valuable reagent for methodological studies in asymmetric synthesis and for exploring new chemical spaces in medicinal chemistry programs.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and metabolic pathways.

Basic Information

Product Name	4-Pentynoicacid,2-Amino-2-Methyl-,(2R)-(9Ci)
CAS No.	403519-98-2
Molecular Formula	C6H9NO2
Molecular Weight	127.14 g/mol
Synonyms	(2R)-2-Amino-2-methyl-4-pentynoic acid; D-2-Amino-2-methyl-4-pentynoic acid; (R)-2-Amino-2-methylpent-4-ynoic acid; 2-Amino-2-methyl-4-pentynoic acid, (R)-; 4-Pentynoic acid, 2-amino-2-methyl-, (2R)-; (R)-2-Amino-2-methyl-4-pentynoate; 403519-98-2; (R)-2-Amino-2-methylpent-4-ynoate
EINECS	Contact for details

Quality Control

Our 4-Pentynoicacid,2-Amino-2-Methyl-,(2R)-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), chiral purity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for GLP or cGMP environments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label/Certificate of Analysis. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.