Description

Cyclopropanecarboxylic Acid, 3-(Fluoroethynyl)-2,2-Dimethyl- (9Ci) is a high-value, fluorinated cyclopropane derivative serving as a sophisticated building block in advanced organic synthesis. Its unique structure, featuring a fluorinated acetylene moiety on a strained cyclopropane ring, makes it a critical intermediate for introducing fluorinated motifs into complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with potentially enhanced metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom can improve lipophilicity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with unique surface properties.
• Fluorine Chemistry & Labeling: An important reagent for introducing 18F or 19F labels into molecules for Positron Emission Tomography (PET) imaging or NMR spectroscopy studies.
• Chemical Biology Probes: Utilized in the design of activity-based probes and molecular tools to study enzyme function and biological pathways.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 3-(Fluoroethynyl)-2,2-Dimethyl- (9Ci)
CAS No.	403507-47-1
Molecular Formula	C8H9FO2
Molecular Weight	156.16 g/mol
Synonyms	3-(Fluoroethynyl)-2,2-dimethylcyclopropanecarboxylic acid; 2,2-Dimethyl-3-(fluoroethynyl)cyclopropanecarboxylic acid; 3-(Fluoroethynyl)-2,2-dimethylcyclopropanecarboxylic Acid; (3-(Fluoroethynyl)-2,2-dimethylcyclopropyl)formic acid; Fluorinated Cyclopropane Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 3-(Fluoroethynyl)-2,2-Dimethyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is supplied with each batch, and custom synthesis to meet specific purity or packaging requirements is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.