Description

2-Aminopyrimidine-5-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. This compound is a critical intermediate for the development of active pharmaceutical ingredients (APIs) and advanced materials, offering precise molecular control. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with targeted modes of action.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as those for OLEDs or conductive polymers.
• Chemical Biology & Diagnostics: Employed in the synthesis of probes, sensors, and labeled compounds for biochemical assays and diagnostic applications.
• Academic & Contract Research: A vital reagent for methodological development in organic synthesis and medicinal chemistry research within academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2-Aminopyrimidine-5-Boronic Acid Pinacol Ester
CAS No.	402960-38-7
Molecular Formula	C11H16BN3O2
Molecular Weight	233.08 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine; 2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-Aminopyrimidine-5-boronic acid pinacol ester; 5-(2-Aminopyrimidin-5-yl)boronic acid pinacol ester; (2-Aminopyrimidin-5-yl)boronic acid pinacol ester; B-(2-Aminopyrimidin-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Aminopyrimidine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.