Description

3-Cyanopyridine-5-Boronic Acid Pinacol Ester is a high-value, multifunctional chemical building block essential for modern synthetic chemistry. Its core value lies in the strategic combination of a boronic ester group, enabling Suzuki-Miyaura cross-coupling reactions, and a cyano-substituted pyridine ring, which serves as a versatile pharmacophore and ligand precursor. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by incorporating the pyridine-cyanoboronate moiety into lead structures.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing sophisticated nitrogen-containing ligands for transition metal catalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers and non-linear optical (NLO) materials.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: Primarily functions as an organoboron reagent in palladium-catalyzed Suzuki-Miyaura couplings to form biaryl and heterobiaryl systems.

Basic Information

Product Name	3-Cyanopyridine-5-Boronic Acid Pinacol Ester
CAS No.	402718-29-0
Molecular Formula	C₁₃H₁₅BN₂O₂
Molecular Weight	242.09 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile; 3-Cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Cyano-5-pyridineboronic acid pinacol ester; 5-Cyanopyridine-3-boronic acid pinacol ester; Nicotinonitrile, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-CN-5-Bpin-Pyridine; 402718-29-0
EINECS	Contact for details

Quality Control

Our 3-Cyanopyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.