Description

Methyl 5-[(Pentafluorophenoxy)Methyl]-2-Furoate is a specialized fluorinated organic building block of significant interest in advanced synthetic chemistry. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research where the introduction of fluorine atoms is crucial for modulating biological activity and stability. It serves the needs of R&D chemists and process development scientists in fine chemical, pharmaceutical, and advanced material sectors seeking to incorporate pentafluorophenoxy motifs into target structures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting enhanced metabolic stability and bioavailability through fluorination.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides where the pentafluorophenoxy group can influence potency and environmental persistence.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated aromatic components in electronic and display materials, contributing to improved dielectric properties and thermal stability.
• Cross-coupling Reactions: Functions as an electrophilic coupling partner in palladium-catalyzed and other metal-mediated cross-coupling reactions to construct complex biaryl systems.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing properties like hydrophobicity, chemical resistance, and optical clarity.
• Proteomics & Bioconjugation: The activated ester-like properties of the furoate moiety make it useful in designing probes, linkers, and reagents for labeling biomolecules.

Basic Information

Product Name	Methyl 5-[(Pentafluorophenoxy)Methyl]-2-Furoate
CAS No.	402600-23-1
Molecular Formula	C13H7F5O4
Molecular Weight	322.19 g/mol
Synonyms	Methyl 5-(pentafluorophenoxymethyl)furan-2-carboxylate; 2-Furancarboxylic acid, 5-[(2,3,4,5,6-pentafluorophenoxy)methyl]-, methyl ester; 5-[(Pentafluorophenoxy)methyl]-2-furoic acid methyl ester; Methyl 5-(perfluorophenoxymethyl)-2-furoate; Pentafluorophenyloxymethyl furancarboxylate methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 5-[(Pentafluorophenoxy)Methyl]-2-Furoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.