Description

2-(Benzofuran-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 402503-13-3 is a high-purity boronic ester derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries seeking to synthesize novel benzofuran-containing molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates containing the benzofuran scaffold.
• Agrochemical Synthesis: Building block for developing novel fungicides, herbicides, and insecticides with enhanced efficacy.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and production of advanced electronic materials and emissive layers.
• Polymer Chemistry: Monomer for creating specialized polymers with tailored optical or electronic properties.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing novel ligands and organometallic catalysts.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	2-(Benzofuran-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	402503-13-3
Molecular Formula	C₁₆H₂₁BO₃
Molecular Weight	272.15 g/mol
Synonyms	2-(Benzofuran-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(2-Benzofuranyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Benzofuran-2-boronic acid pinacol ester; 2-(Benzofuran-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 2-Benzo[b]furan-2-yl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 402503-13-3; Pinacol benzofuran-2-ylboronate
EINECS	Contact for details

Quality Control

Our 2-(Benzofuran-2-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.