Description

3,4-Dimethylphenylboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its enhanced stability and handling properties compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality coupling partners for constructing complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate substituted biphenyl motifs.
• Material Science: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is critical.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new carbon-carbon bond-forming methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	3,4-Dimethylphenylboronic Acid Pinacol Ester
CAS No.	401797-00-0
Molecular Formula	C14H21BO2
Molecular Weight	232.13 g/mol
Synonyms	3,4-Dimethylbenzeneboronic Acid Pinacol Ester; (3,4-Dimethylphenyl)boronic Acid Pinacol Ester; 2-(3,4-Dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (3,4-Dimethylphenyl)boronate; 3,4-Dimethylphenylboronic Acid, Pinacol Ester; 3,4-Xylylboronic Acid Pinacol Ester; B-(3,4-Dimethylphenyl)boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 3,4-Dimethylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.