Description

4-Methoxy-3-(3-Trifluoromethyl-Phenoxymethyl)-Benzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aromatic aldehyde and trifluoromethylphenoxy ether structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its unique scaffold imparts desirable metabolic stability and bioavailability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the trifluoromethyl group for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and advanced organic electronic materials.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory submissions.
• Custom Synthesis and Contract Manufacturing: A starting material for bespoke chemical synthesis services for biotechnology and pharmaceutical clients.

Basic Information

Product Name	4-Methoxy-3-(3-Trifluoromethyl-Phenoxymethyl)-Benzaldehyde
CAS No.	400878-05-9
Molecular Formula	C16H13F3O3
Molecular Weight	310.27 g/mol
Synonyms	4-Methoxy-3-[(3-(trifluoromethyl)phenoxy)methyl]benzaldehyde; 3-[(3-Trifluoromethylphenoxy)methyl]-4-methoxybenzaldehyde; Benzaldehyde, 4-methoxy-3-[[3-(trifluoromethyl)phenoxy]methyl]-; 4-Methoxy-3-(3-trifluoromethylphenoxymethyl)benzaldehyde; CAS 400878-05-9; 3-Trifluoromethylphenoxymethyl-4-methoxybenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxy-3-(3-Trifluoromethyl-Phenoxymethyl)-Benzaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent batch-to-batch quality suitable for sensitive pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.