Description

3-Amino-4-([3-(Trifluoromethyl)Phenyl]Sulfanyl) Benzenecarbonitrile is a high-value, multi-functional organic intermediate featuring a unique combination of an amino group, a benzonitrile core, and a trifluoromethylphenylsulfanyl moiety. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structural motifs confer desirable electronic and physicochemical properties. Industrial and research chemists in the pharmaceutical, agrochemical, and specialty chemical sectors need this material for developing novel compounds with enhanced bioactivity and material performance.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the presence of the trifluoromethyl and amino groups.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the benzonitrile and sulfur linkage contribute to biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transport layers in organic light-emitting diodes (OLEDs) and display technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance thermal stability, chemical resistance, and optical properties.
• Dye & Pigment Intermediate: Utilized in the production of advanced colorants and functional dyes with specific light-absorption characteristics.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Amino-4-([3-(Trifluoromethyl)Phenyl]Sulfanyl) Benzenecarbonitrile
CAS No.	400751-63-5
Molecular Formula	C14H9F3N2S
Molecular Weight	294.30 g/mol
Synonyms	3-Amino-4-[(3-trifluoromethylphenyl)thio]benzonitrile; 4-Amino-3-[(3-(trifluoromethyl)phenyl)sulfanyl]benzonitrile; 3-Amino-4-(3-trifluoromethylphenylsulfanyl)benzonitrile; 3-Amino-4-((3-(trifluoromethyl)phenyl)thio)benzonitrile; Benzonitrile, 3-amino-4-[[3-(trifluoromethyl)phenyl]thio]-; 400751-63-5; α,α,α-Trifluoro-3-[(2-cyano-5-aminophenyl)thio]toluene
EINECS	Contact for details

Quality Control

Our 3-Amino-4-([3-(Trifluoromethyl)Phenyl]Sulfanyl) Benzenecarbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.