Description

2-(1,3-Dioxolan-2-Yl)Biphenyl-3-Carboxylic Acid is a high-purity, functionalized biphenyl derivative featuring a carboxylic acid group and a protected aldehyde moiety. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and inflammation.
• Organic Synthesis Building Block: Used in coupling reactions (e.g., Suzuki, Heck) and as a scaffold for constructing polycyclic aromatic systems and heterocycles.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and organic electronic materials.
• Agrochemical Synthesis: Employed in the research and development of new-generation herbicides and plant growth regulators.

Basic Information

Product Name	2-(1,3-Dioxolan-2-Yl)Biphenyl-3-Carboxylic Acid
CAS No.	400750-15-4
Molecular Formula	C₁₆H₁₄O₄
Molecular Weight	270.28 g/mol
Synonyms	[2-(1,3-Dioxolan-2-yl)phenyl]benzoic acid; 3'-Carboxy-2-(1,3-dioxolan-2-yl)biphenyl; 2-(1,3-Dioxolan-2-yl)-[1,1'-biphenyl]-3-carboxylic acid; Biphenyl-3-carboxylic acid, 2-(1,3-dioxolan-2-yl)-; 2-(1,3-Dioxolan-2-yl)biphenyl-3-carboxylic acid; 2-(2-Phenylphenyl)-1,3-dioxolane-2-carboxylic acid (tautomeric form); CAS 400750-15-4
EINECS	Contact for details

Quality Control

Every batch of 2-(1,3-Dioxolan-2-Yl)Biphenyl-3-Carboxylic Acid is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for pharmaceutical R&D and scale-up. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and IR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.