Description

3-(N,n-Dimethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester is a sophisticated organoboron building block, specifically a protected boronic acid derivative. This compound is essential for facilitating complex cross-coupling reactions, such as the Suzuki-Miyaura reaction, due to its enhanced stability and reactivity profile compared to its free boronic acid counterpart. It is a critical intermediate for researchers and manufacturers in pharmaceutical development and advanced material science, enabling the precise construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for creating biaryl and heterobiaryl structures via Suzuki-Miyaura cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials, liquid crystals, and conductive polymers.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and sensors for biochemical research and diagnostic applications.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis research within university and corporate laboratories.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	3-(N,n-Dimethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester
CAS No.	400727-57-3
Molecular Formula	C15H22BNO3
Molecular Weight	275.15 g/mol
Synonyms	3-(Dimethylcarbamoyl)phenylboronic acid pinacol ester; (3-(Dimethylcarbamoyl)phenyl)boronic acid pinacol ester; 3-(N,N-Dimethylaminocarbonyl)benzeneboronic acid pinacol ester; Pinacol [3-(dimethylcarbamoyl)phenyl]boronate; 3-Carbamoylphenylboronic acid pinacol ester (dimethyl substituted); B-[3-(Dimethylamino)carbonyl]phenyl]-5,5-dimethyl-1,3,2-dioxaborinane; CAS 400727-57-3
EINECS	Contact for details

Quality Control

Our production of 3-(N,n-Dimethylaminocarbonyl)Phenylboronic Acid, Pinacol Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.