Description

1-(Diethoxymethyl)Cyclopropanecarbaldehyde is a versatile and highly functionalized cyclopropane derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an aldehyde and a protected aldehyde (acetal) group on a strained three-membered ring, makes it a valuable precursor for constructing complex molecular architectures. This compound is particularly essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to introduce the cyclopropane motif—a key pharmacophore known to enhance metabolic stability and biological activity.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those containing cyclopropane rings, such as protease inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane group can improve compound efficacy and environmental profile.
• Material Science Precursors: Employed in the development of specialty polymers and functional materials that require rigid, strained-ring components.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes, including cycloadditions and nucleophilic additions, to create complex natural product analogs and novel chemical entities.
• Flavor and Fragrance Chemistry: Acts as an intermediate for synthesizing specific aroma chemicals that benefit from the unique structural properties of the cyclopropane ring.

Basic Information

Product Name	1-(Diethoxymethyl)Cyclopropanecarbaldehyde
CAS No.	400709-86-6
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	Cyclopropanecarbaldehyde, 1-(diethoxymethyl)-; 1-(Diethoxymethyl)cyclopropanecarboxaldehyde; 1-(Diethoxymethyl)cyclopropanecarbaldehyde; 400709-86-6; Cyclopropanecarbaldehyde, 1-[(diethoxymethyl)]-; 1-(Diethoxymethyl)cyclopropane-1-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 1-(Diethoxymethyl)Cyclopropanecarbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency that meets the stringent requirements of research and industrial-scale synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.