Description

3,3-Bis(2-Chloro-6-Fluorobenzyl)-2,4-Pentanedione is a specialized fluorinated diketone compound, serving as a high-value intermediate in advanced organic synthesis. Its unique structure, featuring chloro and fluoro substituents on benzyl groups, makes it a critical building block for creating complex molecules with tailored properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for β-diketone ligands used in coordination chemistry and catalysis, especially for lanthanide and transition metal complexes.
• Material Science Research: Building block for synthesizing advanced organic materials, such as metal-organic frameworks (MOFs) or polymers with specific optical or electronic properties.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry research, enabling structure-activity relationship (SAR) studies and route scouting.
• Fluorine Chemistry: Valuable compound for introducing fluorinated benzyl motifs into target molecules, a common strategy in modern drug design to improve metabolic stability and membrane permeability.

Basic Information

Product Name	3,3-Bis(2-Chloro-6-Fluorobenzyl)-2,4-Pentanedione
CAS No.	400088-51-9
Molecular Formula	C19H16Cl2F2O2
Molecular Weight	385.23 g/mol
Synonyms	3,3-Bis[(2-chloro-6-fluorophenyl)methyl]-2,4-pentanedione; 2,4-Pentanedione, 3,3-bis[(2-chloro-6-fluorophenyl)methyl]-; 3,3-Bis(2-chloro-6-fluorobenzyl)acetylacetone; 1,1'-(2,4-Dioxopentane-1,3-diyl)bis(2-chloro-6-fluorobenzene); Bis(2-chloro-6-fluorobenzyl)acetylacetone; Acetylacetone, bis(2-chloro-6-fluorobenzyl)-; 400088-51-9
EINECS	Contact for details

Quality Control

Our 3,3-Bis(2-Chloro-6-Fluorobenzyl)-2,4-Pentanedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.