Description

Benzeneacetonitrile, α-[[[5,7-Bis(Trifluoromethyl)-1,8-Naphthyridin-2-Yl]Oxy]Methylene]-2,4-Dichloro- (9Ci) is a high-value, multifunctional chemical intermediate characterized by its complex naphthyridine and benzeneacetonitrile core structure. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its unique halogenated and trifluoromethylated architecture. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, or insecticides, leveraging the biological activity of the naphthyridine moiety.
• Material Science Precursor: Serves as a starting material for creating specialized ligands, catalysts, or organic electronic materials.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Item	Details
Product Name	Benzeneacetonitrile, α-[[[5,7-Bis(Trifluoromethyl)-1,8-Naphthyridin-2-Yl]Oxy]Methylene]-2,4-Dichloro- (9Ci)
CAS No.	400087-56-1
Molecular Formula	C20H9Cl2F6N3O2
Molecular Weight	508.21 g/mol
Synonyms	2,4-Dichloro-α-[[[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]oxy]methylene]benzeneacetonitrile; α-(((5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl)oxy)methylene)-2,4-dichlorobenzeneacetonitrile; 2,4-Dichloro-α-(((5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl)oxy)methylene)benzeneacetonitrile; Benzeneacetonitrile, 2,4-dichloro-α-[[[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]oxy]methylene]-
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our rigorous quality testing includes multiple orthogonal analytical methods to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its complex organic structure, prolonged exposure to elevated temperatures, moisture, or direct light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.