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Ethyl 3,4,6-Tri-o-Acetyl-2-Acetamido-2-Deoxy-A-D- Thioglucopyranoside CAS NO 49810-41-5


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CAS No.:49810-41-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl 3,4,6-Tri-o-Acetyl-2-Acetamido-2-Deoxy-A-D- Thioglucopyranoside is a key thioglycoside derivative and a protected glycosyl donor used extensively in carbohydrate chemistry. This compound is valued for its role as a crucial synthetic intermediate in the preparation of complex oligosaccharides and glycoconjugates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic tools, and biochemical probes.

Application

  • Glycosylation Reagent: Acts as a versatile building block for the stereoselective synthesis of S-linked oligosaccharides and glycopeptides.
  • Pharmaceutical Intermediate: Serves as a critical precursor in the research and development of carbohydrate-based drugs and prodrugs.
  • Biochemical Research: Used in enzymatic studies and for the preparation of substrates or inhibitors for glycosidases and glycosyltransferases.
  • Glycoconjugate Synthesis: Essential for creating thioglycoside-linked bioconjugates for applications in targeted drug delivery and vaccine development.
  • Chemical Biology Probes: Employed in the synthesis of activity-based probes to study carbohydrate-processing enzymes in biological systems.
  • Standards and Reference Materials: Supplied as a high-purity standard for analytical method development and quality control in carbohydrate chemistry.

Basic Information

Product Name Ethyl 3,4,6-Tri-o-Acetyl-2-Acetamido-2-Deoxy-A-D- Thioglucopyranoside
CAS No. 49810-41-5
Molecular Formula C₁₆H₂₅NO₉S
Molecular Weight 407.43 g/mol
Synonyms Ethyl 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-α-D-glucopyranoside; 1-Thio-α-D-glucose tetraacetate ethyl glycoside, 2-acetamido-2-deoxy; Ethyl 2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-1-thio-α-D-glucopyranoside; Ethyl 1-Thio-α-D-glucosamine Tetraacetate; 49810-41-5; α-D-Glucopyranoside, ethyl 2-(acetylamino)-2-deoxy-3,4,6-tri-O-acetyl-1-thio-
EINECS Contact for details

Quality Control

Our Ethyl 3,4,6-Tri-o-Acetyl-2-Acetamido-2-Deoxy-A-D- Thioglucopyranoside is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Specific Rotation Contact for details
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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