Description

3-Iodobenzyl Bromide is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its bifunctional nature, featuring both iodine and bromine substituents, makes it a critical intermediate for constructing complex molecular architectures through sequential cross-coupling and functional group transformations. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, ligand synthesis, and the development of specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the iodine and bromine atoms enable further derivatization.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings, where the bromine is typically more reactive, allowing for selective functionalization.
• Ligand and Catalyst Preparation: Employed in the creation of specialized phosphine ligands, N-heterocyclic carbene (NHC) precursors, and other organometallic catalysts.
• Material Science Research: Acts as a building block for organic electronic materials, liquid crystals, and polymers with tailored properties.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for biochemical and diagnostic applications due to its reactive halogens.

Basic Information

Product Name	3-Iodobenzyl Bromide
CAS No.	49617-83-6
Molecular Formula	C7H6BrI
Molecular Weight	296.93 g/mol
Synonyms	1-(Bromomethyl)-3-iodobenzene; m-Iodobenzyl Bromide; (3-Iodophenyl)methyl Bromide; α-Bromo-3-iodotoluene; 3-Iodobenzylbromide; 3-Iodophenylmethyl Bromide; Bromo(3-iodophenyl)methane
EINECS	Contact for details

Quality Control

Our 3-Iodobenzyl Bromide is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.