Description

(S)-2-Hydroxy-2-(Isopropyl)Succinic Acid is a high-purity chiral building block and intermediate of significant value in asymmetric synthesis. Its stereochemically defined structure makes it a critical precursor for the development of active pharmaceutical ingredients (APIs) and advanced fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Catalyst Ligand Precursor: Used in the development and manufacture of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the synthesis of complex, high-value specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Biochemical Research: Used as a standard or reagent in enzymatic studies and metabolic pathway analysis due to its hydroxy acid functionality.
• Polymer Modification: Acts as a monomer or cross-linking agent for introducing chiral centers and functional groups into specialty polymers.

Basic Information

Product Name	(S)-2-Hydroxy-2-(Isopropyl)Succinic Acid
CAS No.	49601-06-1
Molecular Formula	C7H12O5
Molecular Weight	176.17 g/mol
Synonyms	(S)-2-Hydroxy-2-(1-Methylethyl)Butanedioic Acid; (2S)-2-Hydroxy-2-(Propan-2-yl)Succinic Acid; L-2-Hydroxy-2-Isopropylsuccinic Acid; (S)-2-Isopropylmalic Acid; (S)-2-Hydroxy-2-Isopropylbutanedioic Acid; (S)-3-Carboxy-2-Hydroxy-3-Methylbutanoic Acid; (S)-β-Hydroxy-β-Isopropylsuccinic Acid
EINECS	Contact for details

Quality Control

Our (S)-2-Hydroxy-2-(Isopropyl)Succinic Acid is manufactured under a strict quality management system. Each batch is analyzed to ensure high chemical and enantiomeric purity, meeting the rigorous standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.