Description

5-Nitroisoindoline is a versatile nitro-substituted isoindoline derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty chemicals. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with specific functionalities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialized polymers and advanced organic materials.
• Dye and Pigment Manufacturing: Intermediate for producing nitro-aromatic based colorants and photographic chemicals.
• Research & Development: A valuable reagent for academic and industrial R&D in organic synthesis and medicinal chemistry.
• Chemical Synthesis: Employed in multi-step synthetic routes to introduce the nitroisoindoline moiety into more complex molecular architectures.

Basic Information

Product Name	5-Nitroisoindoline
CAS No.	46053-72-9
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	5-Nitro-2,3-dihydro-1H-isoindole; Isoindoline, 5-nitro-; 1H-Isoindole, 2,3-dihydro-5-nitro-; 5-Nitroisoindoline; 5-Nitro-1H-isoindoline; 5-Nitro-2,3-dihydroisoindole; 46053-72-9
EINECS	Contact for details

Quality Control

Our 5-Nitroisoindoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, residual solvent analysis, and identification by spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.