Description

Oxiranemethanamine, n-(1,1-Dimethylethyl)-, (S)- is a high-value, chiral epoxide derivative that serves as a critical chiral building block in advanced organic synthesis. Its primary commercial value lies in its ability to introduce a tert-butyl-protected amino group with defined stereochemistry, enabling the synthesis of complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure APIs, particularly in therapeutic areas requiring high stereoselectivity.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where biological activity is stereospecific.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or epoxidation reactions.
• Fine Chemical Building Block: Employed in academic and industrial R&D for constructing complex natural products and novel molecular architectures.
• Material Science: Potential use in the synthesis of chiral polymers or advanced functional materials with specific optical properties.

Basic Information

Product Name	Oxiranemethanamine, n-(1,1-Dimethylethyl)-, (S)-
CAS No.	45720-12-5
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	(S)-(-)-2-(tert-Butylamino)oxirane; (S)-(-)-2-(tert-Butylamino)methyloxirane; (S)-(-)-N-(tert-Butyl)aziridinemethanol; (S)-(-)-1-tert-Butylamino-2,3-epoxypropane; (S)-(-)-N-tert-Butylglycidylamine; (S)-Glycidyl tert-butylamine; (S)-2-[(1,1-Dimethylethyl)amino]methyl]oxirane; (S)-Tert-butylglycidylamine
EINECS	Contact for details

Quality Control

Our production of Oxiranemethanamine, n-(1,1-Dimethylethyl)-, (S)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All material is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and optical rotation measurement to confirm identity, enantiomeric excess (ee), and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.