Description

1-(Azetidin-1-Yl)Ethanone is a versatile azetidine derivative, a key heterocyclic building block prized for its reactive ketone functionality. This compound is essential for facilitating the synthesis of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material science industries seeking to introduce the azetidine moiety into their target structures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the azetidine ring can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and other advanced chemical transformations.
• Material Science Research: Employed in the synthesis of polymers and functional materials with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-(Azetidin-1-Yl)Ethanone
CAS No.	45467-31-0
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	1-Acetylazetidine; N-Acetylazetidine; Azetidin-1-yl ethanone; 1-Acetyl-azetidine; N-Acetylazacyclobutane; Azetidine, 1-acetyl-; Ethanone, 1-(azetidin-1-yl)-
EINECS	Contact for details

Quality Control

Our 1-(Azetidin-1-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.