Description

Potassium Ethyltrifluoroborate is an organoboron reagent widely used as a stable, air- and moisture-tolerant alternative to boronic acids in cross-coupling reactions. Its significance lies in enabling efficient and reliable synthetic pathways for constructing complex organic molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and process engineers in the fine chemical, pharmaceutical, and advanced materials sectors who require robust and scalable coupling partners.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl halides and the ethyl group, crucial for synthesizing complex intermediates.
• Pharmaceutical Intermediate Synthesis: Used in the production of active pharmaceutical ingredients (APIs) and drug candidates that require ethyl-substituted aromatic or heteroaromatic systems.
• Agrochemical Manufacturing: Employed in the synthesis of herbicides, fungicides, and insecticides where the ethyltrifluoroborate moiety is incorporated into the final product structure.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, ligands, and polymers via palladium-catalyzed coupling.
• Process Chemistry & Scale-up: Valued for its improved stability over boronic acids, making it suitable for large-scale manufacturing processes under less stringent conditions.
• Academic & R&D Laboratories: A staple reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	Potassium Ethyltrifluoroborate
CAS No.	44248-07-9
Molecular Formula	C2H5BF3K
Molecular Weight	139.97 g/mol
Synonyms	Potassium Ethyl-Trifluoroboronate; Ethyltrifluoroborate Potassium Salt; Potassium Ethyltrifluoroborane; Ethyl Potassium Trifluoroborate; Ethyl-BF3K; KEty-BF3; (Ethyl)Trifluoroboronic Acid Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium Ethyltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, NMR purity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for research, development, and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Assay (NMR / Titration)	≥ 97.0%
Purity (NMR)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.