Description

[R,(-)]-Chlorophenylacetic Acid is a high-purity chiral building block essential for asymmetric synthesis. This optically active compound is valued for its role in creating enantiomerically pure intermediates, which are critical for developing pharmaceuticals and agrochemicals with specific biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where the specific stereochemistry can influence efficacy and environmental impact.
• Fine Chemical Production: Serves as a versatile building block for creating complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Industrial Research: Employed in chemical research for developing new synthetic methodologies, catalysis studies, and exploring structure-activity relationships.
• Ligand and Catalyst Preparation: Useful in the synthesis of chiral ligands and organocatalysts for asymmetric transformations.

Basic Information

Product Name	[R,(-)]-Chlorophenylacetic Acid
CAS No.	43195-94-4
Molecular Formula	C8H7ClO2
Molecular Weight	170.59 g/mol
Synonyms	(R)-(-)-2-(4-Chlorophenyl)acetic Acid; (R)-4-Chlorophenylacetic Acid; (R)-p-Chlorophenylacetic Acid; (R)-(-)-p-Chlorophenylacetic Acid; (R)-2-(4-Chlorophenyl)ethanoic Acid; (R)-CPA; (R)-(-)-CPA; (R)-(-)-4-Chlorobenzeneacetic Acid
EINECS	Contact for details

Quality Control

Our [R,(-)]-Chlorophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.