Description

2-Hydroxy-3-Methoxyphenylacetonitrile is a versatile aromatic nitrile derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both phenolic hydroxyl and methoxy substituents, makes it a valuable building block for constructing complex molecules with specific functionalities. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzofuran or catechol-like structures.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and advanced polymer modifiers.
• Biochemical Research: Utilized as a probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Flavor and Fragrance Industry: Intermediate for the synthesis of complex aroma chemicals.

Basic Information

Product Name	2-Hydroxy-3-Methoxyphenylacetonitrile
CAS No.	42973-56-8
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	2-Hydroxy-3-methoxybenzyl cyanide; (2-Hydroxy-3-methoxyphenyl)acetonitrile; 3-Methoxysalicylonitrile; o-Vanillonitrile; 2-Cyano-1-(2-hydroxy-3-methoxyphenyl)ethane; 42973-56-8
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Methoxyphenylacetonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.