Description

1-(4-Trifluoromethyl-Phenyl)-Pentan-1-One is a specialized fluorinated aromatic ketone building block. This compound is valued for its trifluoromethyl group, which imparts unique electronic and lipophilic properties critical for advanced material and pharmaceutical synthesis. It serves as a key intermediate for researchers and manufacturers in the agrochemical, pharmaceutical, and material science industries seeking to incorporate fluorine into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the bioisosteric and metabolic stability properties of the trifluoromethyl group.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorine substitution enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Organic Synthesis & Chemical Research: A versatile reagent for Friedel-Crafts acylation and subsequent functionalization reactions in academic and industrial R&D laboratories.
• Polymer Modifier: Can be incorporated into polymer chains to alter thermal stability, solubility, and optical properties of high-performance engineering plastics.

Basic Information

Product Name	1-(4-Trifluoromethyl-Phenyl)-Pentan-1-One
CAS No.	42916-66-5
Molecular Formula	C12H13F3O
Molecular Weight	230.23 g/mol
Synonyms	4'-Trifluoromethyl Valerophenone; 1-Pentanone, 1-[4-(trifluoromethyl)phenyl]-; 4-(Trifluoromethyl)valerophenone; p-Trifluoromethylvalerophenone; Valerophenone, 4'-trifluoromethyl-; α-Pentyl-4-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our production of 1-(4-Trifluoromethyl-Phenyl)-Pentan-1-One adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for fine chemical and pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (typically by GC/HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.