Description

2-Acetyl-3-Bromothiophene is a high-value brominated thiophene derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique molecular structure, featuring both an acetyl and a bromine substituent on the thiophene ring, makes it an essential intermediate for constructing complex heterocyclic compounds. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) agents and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene scaffold.
• Material Science: Serves as a monomer or building block for creating conjugated polymers and organic semiconductors used in electronic devices.
• Chemical Research: Employed in academic and industrial R&D for palladium-catalyzed cross-coupling reactions, such as Suzuki and Heck reactions, to create complex molecular architectures.
• Ligand and Catalyst Development: Utilized to synthesize novel ligands for metal complexes used in homogeneous catalysis.
• Fine Chemical Production: Acts as an intermediate for the manufacture of dyes, pigments, and other specialty chemicals.

Basic Information

Product Name	2-Acetyl-3-Bromothiophene
CAS No.	42877-08-7
Molecular Formula	C6H5BrOS
Molecular Weight	205.07 g/mol
Synonyms	3-Bromo-2-acetylthiophene; 1-(3-Bromothiophen-2-yl)ethanone; 2-Acetyl-3-bromothiophene; 3-Bromo-2-thienyl methyl ketone; 2-Acetyl-3-bromo-thiophene; 3-Bromo-2-acetyl-thiophene; Ethanone, 1-(3-bromo-2-thienyl)-
EINECS	Contact for details

Quality Control

Our 2-Acetyl-3-Bromothiophene is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.