Description

2-(3-Butyn-1-Yl)-2-Methyl-1,3-Dioxolane is a versatile acetal-protected alkyne building block, essential for advanced organic synthesis. Its core value lies in providing a masked terminal alkyne functionality that is stable under a wide range of reaction conditions, enabling precise and complex molecular construction. This compound is particularly needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediates: A key synthon for constructing complex molecular architectures via Sonogashira, Huisgen cycloaddition (click chemistry), and other cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require alkyne-containing scaffolds.
• Material Science & Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored optical, electronic, or mechanical properties.
• Ligand & Catalyst Development: Employed in the synthesis of novel phosphine or N-heterocyclic carbene (NHC) ligands containing alkyne handles for metal coordination.
• Chemical Biology & Bioconjugation: Acts as a probe precursor for labeling biomolecules (proteins, nucleic acids) via bioorthogonal click chemistry reactions.
• Organic Electronic Materials: A building block for π-conjugated systems used in OLEDs, organic photovoltaics, and semiconductor materials.

Basic Information

Item	Details
Product Name	2-(3-Butyn-1-Yl)-2-Methyl-1,3-Dioxolane
CAS No.	42541-87-7
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	2-Methyl-2-(3-butynyl)-1,3-dioxolane; 2-(But-3-yn-1-yl)-2-methyl-1,3-dioxolane; 2-Methyl-2-(but-3-yn-1-yl)-1,3-dioxolane; 4-(2-Methyl-1,3-dioxolan-2-yl)but-1-yne; Acetonide of 5-hexyn-2-one; 5-Hexyn-2-one ethylene ketal; 5-Hexyn-2-one cyclic ethylene ketal
EINECS	Contact for details

Quality Control

Our 2-(3-Butyn-1-Yl)-2-Methyl-1,3-Dioxolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.